The Wilson Lawrence Blog

Most Cancer Treatments Do Little to Help Mesothelioma Patients, However Gene Therapy Could Provide a Hope

Oncologists and other cancer doctors decide what type of treatment to go with with every patient. The options are endless. There exists no standard treatment regimen for pleural mesothelioma cancer sufferers. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Traditional treatments for cancer are surgery (removing the tumor and surrounding tissue), radiation (killing the cancerous cells with radiation), and chemotherapy (poisoning the cancerous cells.) Each one of these methods have problems. Patients with mesothelioma have not responded well to traditional radiation therapy. Researches, concerned about damage to healthy tissue, are looking for ways to aim radiation directly at tumors.

The mesothelial tissue around the tumor is removed by surgery. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different mixtures of these drugs have not been successful. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.

Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. The new drug pemetrexed (brand name Alimta) has shown good results in extending life with mesotheliomas..

Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Mesothelioma patients sometimes become involved in clinical trials in this area, and see benefits.

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